Why is it that most major universities maps are still relegated to the old scanned paper copy? Check out the beauty that is University of Michigan's Campus map. It's amazing that a major university still uses GIF images for their campus maps.
Now, they know what mapping is, check out their cool transit services. There is even a 3D Atlas of Ann Arbor in Google Earth.
It's not hard to make this into a more usable dynamic map. I used the MetaCarta's Map Rectifier to take the campus map image, rectify it using several control points (intersections and circles work great for this) and created a slippy campus map.

You can play with the actual Campus Map here on MapSomething. The next steps would be searchable campus directory, click on buildings to get info on rooms, open times, phone numbers, a way to upload your schedule and have it plan out your route, etc.
Maybe I should send this on over to the School of Information or the Community Information Corps